Adaptive immune response generates T cell and B cell receptors (TCRs and BCRs) which together comprise an organism’s immune repertoire.
Immune repertoire analysis has a wide range of applications including cancer diagnosis and treatment, gene therapy development and infectious diseases.
High-throughput technologies have emerged which allow comprehensive monitoring of the immune repertoire over time.Get in touch today
Over the years, several techniques have been developed to analyze immune repertoires. Although we have progressed from low-throughput to high-throughput analysis techniques, several challenges remain. Streamlined experimental pipelines for unique applications and customized bioinformatics tools for data analysis remain underdeveloped.
At GeneWerk, we offer PCR- and target enrichment sequencing-based approaches for customized, high-throughput and simultaneous analysis of T cell and B cell receptors from a wide range of sample input material.
We offer target enrichment sequencing (TES) as a robust, fast, and cost-effective approach for the analysis of TCR or BCR chains from the same input material.
At GeneWerk, we offer Rapid Amplification of cDNA Ends (RACE)-PCR combined with switch-oligo nested PCR as an alternative to TES to amplify and sequence the entire immune repertoire from limited sample material.
Read our latest press releases and announcements below.
GeneWerk will expand capabilities to meet rapidly growing demand for cell and gene therapy...